How to get Mammary Gland TOP2A Gene Detection kit?

DNA topoisomerase 2-alpha is an agitator that in bodies is encoded by the TOP2A gene.
Mammary Gland TOP2A Gene encodes a DNA topoisomerase, an agitator that controls and alters the topologic states of DNA during transcription. This nuclear agitator is complex in processes such as chromosome condensation, chromatid separation, and the abatement of torsional accent that occurs during DNA archetype and replication. It catalyzes the brief breaking and rejoining of two strands of bifold DNA which allows the strands to canyon through one another, appropriately altering the cartography of DNA. Two forms of this agitator abide as acceptable articles of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this agitator functions as the ambition for several anticancer agents and a array of mutations in this gene accept been associated with the development of biologic resistance. Reduced action of this agitator may aswell play a role in ataxia-telangiectasia.
Function of TOP2A Gene
protein C-terminus binding; DNA topoisomerase (ATP-hydrolyzing) activity; DNA-dependent ATPase activity; ubiquitin binding; structure-specific DNA binding; protein homodimerization activity; histone deacetylase binding; nucleotide binding; drug binding; protein binding; enzyme binding; DNA binding; protein kinase C binding; protein heterodimerization activity; sequence-specific DNA binding; chromatin binding; ATP binding
Biological Process: response to drug; mitotic recombination; positive regulation of viral genome replication; DNA topological change; phosphoinositide-mediated signaling; positive regulation of apoptosis; sister chromatid segregation; apoptotic chromosome condensation; DNA repair; DNA ligation; chromosome segregation; positive regulation of retroviral genome replication; regulation of transcription, DNA-dependent; resolution of meiotic joint molecules as recombinants; DNA-dependent DNA replication; DNA replication; response to DNA damage stimulus; aging
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