What is PTPN3?

The protein encoded by PTPN3 is a affiliate of the protein tyrosine phosphatase (PTP) family. PTPs are accepted to be signaling molecules that adapt a array of cellular processes including corpuscle growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP area and an N-terminal area akin to the bandage 4.1 superfamily of cytoskeletal-associated proteins. P97, a corpuscle aeon regulator complex in a array of film accompanying functions, has been apparent to be a substrate of this PTP. This PTP was aswell begin to collaborate with, and be adapted by adaptor protein 14-3-3 beta. Several alternatively spliced archetype variants encoding altered isoforms accept been begin for this gene.
PTPN3 May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. Note: This description may include information from UniProtKB.
Molecular Function: protein binding; hydrolase activity; phosphotyrosine binding; cytoskeletal protein binding; protein tyrosine phosphatase activity; ATPase binding
Biological Process: negative regulation of mitotic cell cycle; protein amino acid dephosphorylation; negative regulation of membrane protein ectodomain proteolysis
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